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Intracytoplasmic Sperm Injection (ICSI)

The ICSI method is one of the versions of IVF and is used in severe cases of male infertility. This procedure is very effective even after a vasectomy or with a congenital defect such as the absence of deferent ducts.

How is ICSI different from IVF?

The fundamental difference between the two methods is in the fact that only one sperm is needed to perform an intracytoplasmic injection. Specialists at the medical centre will give you detailed explanations about medical indications for the procedure as well as how the procedure is conducted.


For the most part the stages of the IVF and ICSI procedures coincide with each other. There are, however, some important differences. The thing is that during a standard in vitro fertilization procedure the sperm have the same task as during the process of natural conception: i.e., to fertilize the egg on their own. In this particular programme, a sperm that was chosen by an embryologist is injected into an oocyte’s cytoplasm with the help of a microscopic needle. In the process of preparing for the procedure, the specialists use a special reagent that breaks up the egg’s protective layers, allowing the sperm to enter inside.

How is the procedure conducted?

An embryologist selects a sperm that has normal structure and immobilizes it by cutting off its tail. Afterwards the sperm is aspirated into a very long glass micropipette and injected into an egg’s cytoplasm. Meanwhile, the oocyte is being held in place with the help of a special microscopic suction cup. The probability of damaging the egg is extremely small, no greater than one percent. Nevertheless, such a probability does exist, and that is exactly why it makes sense to only trust highly qualified professionals to conduct treatment using this method. In choosing where to perform ICSI, look at the rate of effectiveness of the procedure at a specific clinic, the experience of the doctors, and the scientific and technical resources of a particular medical facility.

The probability of becoming pregnant

According to statistical data, pregnancy after the procedure occurs in approximately thirty to sixty out of one hundred women. That said, normal development of an embryo after its transfer into a female patient’s uterus is observed in 90-95% of cases.

Why is the cost different?

In asking about the cost of IVF and ICSI the patients wish to know the reason for the difference in price. We have already described how IVF differs from ICSI, and it is obvious that additional operations are required to conduct the latter procedure. And that is the reason for the higher cost of this method in comparison with IVF.

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In this section we would like to talk about how one can find a surrogate mother, which methods of searching for surrogate mothers are the most preferred, and which methods are positively not recommended to be used.

Egg donorship

Egg donorship is used in the course of infertility treatment in cases when a female patients ovarian reserve is depleted (during menopause, for example), or the oocytes are of poor quality and cannot be used in an IVF cycle. As in the case of a surrogate mother search there are several solutions to this problem.


In vitro fertilization technology has been in use all over the world over the past several decades. The chances of becoming pregnant with the help of IVF are increasing, because ART methods are constantly being improved. Nowadays pregnancy after IVF occurs on average in forty percent of cases.